Cancer immunotherapy has produced some of medicine’s most dramatic success stories over the past decade. But for every patient whose tumors vanish, several others see little or no benefit. One class of drugs in particular, called CD40 agonist antibodies, promised to supercharge the immune system’s ability to hunt and destroy cancer cells. For more than…
Glioblastoma is one of the most aggressive and devastating brain cancers, often leaving patients and families with few options. Traditional treatments—surgery, chemotherapy, and radiation—can slow the disease, but survival rates remain low. Now, researchers at the University of Florida are testing a new approach: a personalized mRNA cancer vaccine designed to reprogram the immune system…
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